BDBM50279510 CHEMBL4170201

SMILES COc1ccc(NC(=O)N[C@H](Cc2ccc(cc2)C#N)C(=O)NCC2(CC2)c2ccc(F)c(Cl)c2)cc1

InChI Key InChIKey=XGGVKMKGFJGDRC-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279510   

TargetfMet-Leu-Phe receptor(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50279510(CHEMBL4170201)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human FPR1 expressed in human HL60 cells assessed as induction of calcium mobilization measured every 5 secs for 240 secs by Fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2020
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50279510(CHEMBL4170201)
Affinity DataEC50:  730nMAssay Description:Agonist activity at FPR2 in human neutrophils assessed as induction of calcium mobilization measured every 5 secs for 240 secs by Fluo-4-AM dye based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2020
Entry Details Article
PubMed
TargetN-formyl peptide receptor 2(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50279510(CHEMBL4170201)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human FPR2 expressed in human HL60 cells assessed as induction of calcium mobilization measured every 5 secs for 240 secs by Fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2020
Entry Details Article
PubMed