BDBM50279560 CHEMBL448513::N-{4-[(1S,2S,4R,5R)-2,4-Diguanidino-5-(4-guanidino-naphthalen-1-yloxy)-cyclohexyloxy]-3-guanidino-phenyl}-guanidine

SMILES NC(N)=Nc1ccc(O[C@H]2C[C@@H](Oc3ccc(N=C(N)N)c4ccccc34)[C@H](N=C(N)N)C[C@@H]2N=C(N)N)c(N=C(N)N)c1

InChI Key InChIKey=HPNPLIXVYNDMDL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279560   

TargetFurin(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279560BDBM50279560(N-{4-[(1S,2S,4R,5R)-2,4-Diguanidino-5-(4-guanidino...)
Affinity DataKi:  404nMAssay Description:Inhibition of Recombinant vaccinia-expressed furin (unknown origin) using Pyr-RTKR-MCA as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFurin(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279560BDBM50279560(N-{4-[(1S,2S,4R,5R)-2,4-Diguanidino-5-(4-guanidino...)
Affinity DataKi:  404nMAssay Description:Inhibition of human recombinant furin-dependent anthrax protective antigen processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed