BDBM50279584 CHEMBL485694::N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-phenoxy)-cyclohexyl]-guanidine

SMILES NC(N)=Nc1ccc(O[C@H]2C[C@@H](Oc3ccc(N=C(N)N)cc3)[C@H](N=C(N)N)C[C@@H]2N=C(N)N)cc1

InChI Key InChIKey=QZVCIVTYONPXJV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279584   

TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279584BDBM50279584(N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant furin-dependent anthrax protective antigen processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279584BDBM50279584(N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-...)
Affinity DataKi:  12nMAssay Description:Inhibition of Recombinant vaccinia-expressed furin (unknown origin) using Pyr-RTKR-MCA as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed