BDBM50279605 CHEMBL487946::N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(5-guanidino-pyridin-2-yloxy)-cyclohexyl]-guanidine

SMILES [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(cn1)\[#7]=[#6](\[#7])-[#7])-[#8]-c1ccc(cn1)\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=CNCLUTAORIAEFW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279605   

TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50279605(N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(5-guanidino-...)
Affinity DataKi:  42nMAssay Description:Inhibition of human recombinant furin-dependent anthrax protective antigen processingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFurin(Human)
Mahidol University

Curated by ChEMBL
LigandPNGBDBM50279605(N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(5-guanidino-...)
Affinity DataKi:  42nMAssay Description:Inhibition of Recombinant vaccinia-expressed furin (unknown origin) using Pyr-RTKR-MCA as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed