BDBM50279698 2-(4-Methyl-2-methylamino-thiazol-5-yl)-3-o-tolyl-3H-quinazolin-4-one::CHEMBL515276

SMILES CNc1nc(C)c(s1)-c1nc2ccccc2c(=O)n1-c1ccccc1C

InChI Key InChIKey=CNOZEZOCALUISD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279698   

TargetTranscription factor Jun(Human)
B.V. Patel Pharmaceutical Education and Research Development Centre

Curated by ChEMBL
LigandPNGBDBM50279698(2-(4-Methyl-2-methylamino-thiazol-5-yl)-3-o-tolyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation treated 24 hrs before TNFalpha cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
B.V. Patel Pharmaceutical Education and Research Development Centre

Curated by ChEMBL
LigandPNGBDBM50279698(2-(4-Methyl-2-methylamino-thiazol-5-yl)-3-o-tolyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed