BDBM50279733 CHEMBL4174082
SMILES N#Cc1cccc(c1)-c1nc(Nc2cc([nH]n2)C2CC2)c2ccccc2n1
InChI Key InChIKey=BKVJIBAADPVALB-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50279733
Affinity DataKi: 9nMAssay Description:Inhibition of recombinant GSK3beta (unknown origin) using HSSPHQ(Sp)EDEEE as substrate by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant CDK2/cyclin A (unknown origin) using MAHHRSPRKRAKKK as substrate by pyruvate kinase-lactate dehydrogenase coupled assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of hog kidney renin at 10e-9 M concentrationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PknB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of Mycobacterium tuberculosis PknB (M1 to G279 residues) expressed in Escherichia coli BL21 (DE3) cells using [T-33P]ATP as substrate afte...More data for this Ligand-Target Pair