BDBM50280521 (4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-2-yl)-allyl]-dihydro-furan-2-one::CHEMBL22923

SMILES C[C@@H]1OC(=O)C[C@H]1C\C=C\[C@H]1CCCCN1C

InChI Key InChIKey=GWRXGSVCPYKRNL-CAJTZJJPSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50280521   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  4.40E+3nMAssay Description:Dissociation constant of the compound for human Muscarinic acetylcholine receptor M2 was determined.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  1.21E+3nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  9.70E+3nMAssay Description:Displacement of [3H]-QNB from muscarinic receptor 1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  1.21E+3nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  9.70E+3nMAssay Description:Dissociation constant of the compound for human Muscarinic acetylcholine receptor M1 was determined.More data for this Ligand-Target Pair
In DepthDetails Article