BDBM50280720 CHEMBL425325::{6-Fluoro-9-[3-(4-pyridin-3-yl-butoxy)-benzyl]-2,3,4,9-tetrahydro-1H-carbazol-1-yl}-acetic acid

SMILES OC(=O)CC1CCCc2c1n(Cc1cccc(OCCCCc3cccnc3)c1)c1ccc(F)cc21

InChI Key InChIKey=MIIIWVNAZRSKJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280720   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280720({6-Fluoro-9-[3-(4-pyridin-3-yl-butoxy)-benzyl]-2,3...)
Affinity DataIC50: 100nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article