BDBM50281428 8-(4-Fluoro-benzyl)-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5]dec-2-en-4-one; hydrochloride::CHEMBL545695

SMILES Fc1ccc(CN2CCC3(CC2)OC=C(C3=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=OTBGSMLTKVRBTA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281428   

LigandPNGBDBM50281428(8-(4-Fluoro-benzyl)-3-(4-fluoro-phenyl)-1-oxa-8-az...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281428(8-(4-Fluoro-benzyl)-3-(4-fluoro-phenyl)-1-oxa-8-az...)
Affinity DataKi:  1.66E+3nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article