BDBM50281524 CHEMBL123713::[3,3-Diethyl-5-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-pyrrolidin-(2Z)-ylidene]-acetic acid ethyl ester

SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC1(CC)CC

InChI Key InChIKey=JNYGGWPRWHVUGL-JCMHNJIXSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281524   

TargetType-1 angiotensin II receptor(Rabbit)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50281524(CHEMBL123713 | [3,3-Diethyl-5-oxo-1-[2'-(1H-tetraz...)
Affinity DataKd:  12.6nMAssay Description:Antagonist activity at angiotensin AT1 receptor in rabbit aortic strip assessed as inhibition of angiotensin 2-induced contractile responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetType-1 angiotensin II receptor(Rabbit)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50281524(CHEMBL123713 | [3,3-Diethyl-5-oxo-1-[2'-(1H-tetraz...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at angiotensin AT1 receptor in rabbit adrenal cortex assessed as inhibition of angiotensin 2-induced contractile responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetType-1 angiotensin II receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50281524(CHEMBL123713 | [3,3-Diethyl-5-oxo-1-[2'-(1H-tetraz...)
Affinity DataIC50:  100nMAssay Description:Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...More data for this Ligand-Target Pair
In DepthDetails Article