BDBM50281723 CHEMBL34335::[2-Oxo-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetic acid tert-butyl ester

SMILES Cc1cccc(NC(=O)NC2CCc3ccccc3N(CC(=O)OC(C)(C)C)C2=O)c1

InChI Key InChIKey=BEXFBMPJEUUUPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281723   

LigandPNGBDBM50281723([2-Oxo-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-ben...)
Affinity DataIC50: 18nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281723([2-Oxo-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-ben...)
Affinity DataIC50: 110nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281723([2-Oxo-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-ben...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Cholecystokinin type B receptor in guinea pig cerebral cortex using [125 I ]- CCK-8 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281723([2-Oxo-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-ben...)
Affinity DataIC50: 140nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article