BDBM50282235 CHEMBL4174166

SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@H](OC(=O)c1c(F)c(F)c(N=[N+]=[N-])c(F)c1F)[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)CC[C@]12C

InChI Key InChIKey=AWNCAUIWMWPQMB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282235   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50282235(CHEMBL4174166)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of human GABAA receptor alpha1beta2gamma2L expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50282235(CHEMBL4174166)
Affinity DataEC50:  500nMAssay Description:Positive allosteric modulation of human GABAA receptor alpha1beta2gamma2L expressed in Xenopus laevis oocytes assessed as potentiation of GABA chlori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50282235(CHEMBL4174166)
Affinity DataEC50:  770nMAssay Description:Displacement of [3H]muscimol from human GABAA receptor alpha1beta3gamma2 expressed in HEK293 TetR cell membranes after 1 hr by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed