BDBM50282705 CHEMBL290669::N-Benzyl-N-{2-isopropyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-benzamide

SMILES CC(C)c1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)c1ccccc1

InChI Key InChIKey=AXBAKKNMVBYNSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282705   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282705(CHEMBL290669 | N-Benzyl-N-{2-isopropyl-4-oxo-3-[2'...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensinogen(Rat)
Mnr College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50282705(CHEMBL290669 | N-Benzyl-N-{2-isopropyl-4-oxo-3-[2'...)
Affinity DataIC50:  0.220nMAssay Description:Binding affinity to AT2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282705(CHEMBL290669 | N-Benzyl-N-{2-isopropyl-4-oxo-3-[2'...)
Affinity DataIC50:  0.350nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article