BDBM50282782 CHEMBL297327::{(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-ethylcarbamoyl]-1-methyl-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@](C)(Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCCCCCCCCO

InChI Key InChIKey=ZYOSMLUSASXSFL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282782   

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetNeuromedin-K receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 6.16E+3nMAssay Description:Binding affinity for NK2 receptor binding sites in membranes prepared from hamster urinary bladder by using [125I]NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282782({(S)-1-[(R)-1-(8-Hydroxy-octylcarbamoyl)-2-phenyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for NK1 receptor binding sites in human lymphoma IM9 cells by using [125I]-Bolton-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article