BDBM50282961 5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-piperazin-1-yl}-pyrimidine::CHEMBL300150

SMILES Fc1ccc(OCCCN2CCN(CC2)c2ncc(F)cn2)cc1

InChI Key InChIKey=RTKTZAFQKPVZCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282961   

LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50: 89nMAssay Description:In vitro binding affinity towards sigma receptor by the displacement of [3H]PPP from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50: 141nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282961(5-Fluoro-2-{4-[3-(4-fluoro-phenoxy)-propyl]-pipera...)
Affinity DataIC50: 145nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article