BDBM50282971 4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butyl}-benzenesulfonamide::CHEMBL300351

SMILES Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(F)cn1)NS(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=IKASFGAIJDOSDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282971   

LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50: 1.52E+3nMAssay Description:In vitro binding affinity towards sigma receptor by the displacement of [3H]PPP from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50: 1.81E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282971(4-Fluoro-N-{1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyr...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article