BDBM50283051 (Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyridin-3-yl-tetrahydro-furan-3-yl]-hept-4-enoic acid::CHEMBL63040

SMILES OC(=O)CC\C=C/CC[C@H]1[C@H](CO[C@@H]1c1cccnc1)OCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NMJYFIAGWNELHF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283051   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 4.30nMAssay Description:In vitro inhibition against thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 4.30nMAssay Description:In vitro inhibition against thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition against thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 27nMAssay Description:In vitro thromboxane receptor antagonist against U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 28nMAssay Description:In vitro thromboxane receptor antagonist against U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283051((Z)-7-[(2S,3R,4R)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 28nMAssay Description:In vitro thromboxane receptor antagonist against U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article