BDBM50283053 (Z)-7-[(2R,3R,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyridin-3-yl-tetrahydro-furan-3-yl]-hept-4-enoic acid::CHEMBL294353

SMILES OC(=O)CC\C=C/CC[C@H]1[C@@H](CO[C@H]1c1cccnc1)OCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NMJYFIAGWNELHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283053   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283053((Z)-7-[(2R,3R,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition against thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283053((Z)-7-[(2R,3R,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 820nMAssay Description:In vitro thromboxane receptor antagonist against U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article