BDBM50283304 2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(N-isopropyl-N-methyl-aminocarbonylamino)-3H-quinazolin-4-one::CHEMBL75401

SMILES CC(C)CCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(C)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1

InChI Key InChIKey=LNKVMRUZWGLRSF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283304   

LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 0.580nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 0.720nMAssay Description:In vivo inhibitory concentration against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 1.10nMAssay Description:In vivo inhibitory concentration against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 2.30nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 13nMAssay Description:In vivo inhibitory concentration against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283304(2-methyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyl...)
Affinity DataIC50: 27nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article