BDBM50283449 5-(4-Hydroxy-3,5-dimethyl-phenyl)-6-methyl-2-{2-[4-(4-methyl-pyridin-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-8-ol::CHEMBL305825

SMILES Cc1c(-c2cc(C)c(O)c(C)c2)n2CC(CCN3CCN(CC3)c3cc(C)ccn3)Oc3cc(O)cc1c23

InChI Key InChIKey=PWQSGDXLYIZACP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283449   

LigandPNGBDBM50283449(5-(4-Hydroxy-3,5-dimethyl-phenyl)-6-methyl-2-{2-[4...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against 5-lipoxygenase in guinea pig leukocytes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283449(5-(4-Hydroxy-3,5-dimethyl-phenyl)-6-methyl-2-{2-[4...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against 5-lipoxygenase in rat neutrophils as inhibition of A 23,187-induced LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article