BDBM50284768 (S)-2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-3-methyl-butyrylamino}-propionylamino)-hexanoic acid::CHEMBL431124
SMILES CCCC[C@H](NC(=O)[C@@H](Cc1c([nH]c2ccccc12)C#N)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C(C)C)C(O)=O
InChI Key InChIKey=WTIMYTIFDDIBIP-DBKYNLIOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50284768
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Functional inhibition of ET-1 induced [Ca2+] increase in human neuroblastoma-derived SK-N-MC cells, which express Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Functional inhibition of ET-1 induced [Ca2+] increase in human Girardi heart (hGH) cells, which express Endothelin B receptorMore data for this Ligand-Target Pair