BDBM50284873 1-(2,6-Diisopropyl-phenyl)-3-[(4R,5R)-2-(4-hydroxy-phenyl)-4,5-dimethyl-[1,3]dioxolan-2-ylmethyl]-urea::CHEMBL291052

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(O[C@H](C)[C@@H](C)O1)c1ccc(O)cc1

InChI Key InChIKey=BNHLITZQJDEFQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284873   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284873(1-(2,6-Diisopropyl-phenyl)-3-[(4R,5R)-2-(4-hydroxy...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT) in microsomes from cholesterol-fed rabbit intestinal mucosaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284873(1-(2,6-Diisopropyl-phenyl)-3-[(4R,5R)-2-(4-hydroxy...)
Affinity DataIC50: 119nMAssay Description:Inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT) in microsomes from monkey liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284873(1-(2,6-Diisopropyl-phenyl)-3-[(4R,5R)-2-(4-hydroxy...)
Affinity DataIC50: 119nMAssay Description:Inhibitory activity against acyl-CoA: cholesterol acyltransferase (ACAT) in microsomes from monkey liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article