BDBM50284965 1-[3-(2-Chloro-phenyl)-3H-imidazo[4,5-b]pyridin-2-yl]-3-(2,6-diisopropyl-phenyl)-urea::CHEMBL55870

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2cccnc2n1-c1ccccc1Cl

InChI Key InChIKey=XGBGXZAHOCDEKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284965   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284965(1-[3-(2-Chloro-phenyl)-3H-imidazo[4,5-b]pyridin-2-...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibitory activity towards acyl CoA cholesterol acyltransferase (ACAT) of cholesterol-fed rabbits by the displacement of [14C]oleolyl-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article