BDBM50284968 1-[1-(4-Chloro-phenyl)-1H-benzoimidazol-2-yl]-3-(2,6-diisopropyl-phenyl)-urea::CHEMBL53524

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=FSHLHNXMNVQREI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284968   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284968(1-[1-(4-Chloro-phenyl)-1H-benzoimidazol-2-yl]-3-(2...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity towards acyl CoA cholesterol acyltransferase (ACAT) of cholesterol-fed rabbits by the displacement of [14C]oleolyl-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article