BDBM50284972 1-(2,6-Diisopropyl-phenyl)-3-[1-(2-methoxy-phenyl)-1H-benzoimidazol-2-yl]-urea::CHEMBL53537

SMILES COc1ccccc1-n1c(NC(=O)Nc2c(cccc2C(C)C)C(C)C)nc2ccccc12

InChI Key InChIKey=GCYHJDAGQVPRHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284972   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284972(1-(2,6-Diisopropyl-phenyl)-3-[1-(2-methoxy-phenyl)...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity towards acyl CoA cholesterol acyltransferase (ACAT) of cholesterol-fed rabbits by the displacement of [14C]oleolyl-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article