BDBM50284979 1-[1-(3-Chloro-phenyl)-1H-benzoimidazol-2-yl]-3-(2,6-diisopropyl-phenyl)-urea::CHEMBL416485

SMILES CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1cccc(Cl)c1

InChI Key InChIKey=MSWZPFQOAIQKFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50284979   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284979(1-[1-(3-Chloro-phenyl)-1H-benzoimidazol-2-yl]-3-(2...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity towards acyl CoA cholesterol acyltransferase (ACAT) of cholesterol-fed rabbits by the displacement of [14C]oleolyl-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article