BDBM50285198 CHEMBL67131::[(5S,11S,14S)-21-Fluoro-11-(3-guanidino-propyl)-14-isopropyl-12-methyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaaza-bicyclo[15.3.1]henicosa-1(20),17(21),18-trien-5-yl]-acetic acid

SMILES CC(C)[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)N(C)C1=O)c2F

InChI Key InChIKey=UMBVVGYRMZYGDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285198   

TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285198([(5S,11S,14S)-21-Fluoro-11-(3-guanidino-propyl)-14...)
Affinity DataIC50: 4nMAssay Description:Inhibition of platelet aggregation in vitro using fibrinogen binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285198([(5S,11S,14S)-21-Fluoro-11-(3-guanidino-propyl)-14...)
Affinity DataIC50: 20nMAssay Description:Inhibition of platelet aggregation using human platelet rich plasma (hPRP) assay (200microL, 2-3 x 10e 8 platelets/mL, n=1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article