BDBM50285227 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene::CHEMBL305060

SMILES CS(=O)(=O)c1ccc(cc1)-c1ccsc1-c1ccc(F)cc1

InChI Key InChIKey=DTVXNOVVMAMQNU-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50285227   

TargetProstaglandin G/H synthase 2(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50285227(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-t...)
Affinity DataKi:  250nMAssay Description:Binding affinity to COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50285227(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50:  4.90E+5nMAssay Description:Compound was evaluated for inhibitory activity against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article

TargetProstaglandin G/H synthase 2(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50285227(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50:  8.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285227(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human COX-1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetProstaglandin G/H synthase 2(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50285227(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-t...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against human COX-2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article