BDBM50285776 CHEMBL4172309

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2CNC(=O)N1CCc2[nH]nnc2C1)C(=O)OCc1cc(cc(c1)C(=O)OC(F)(F)F)C#N

InChI Key InChIKey=KLTYKZYRGMOAQZ-OSYLJGHBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285776   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285776(CHEMBL4172309)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285776(CHEMBL4172309)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285776(CHEMBL4172309)
Affinity DataIC50:  33nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed