BDBM50286102 CHEMBL353736::Morphinan Cyclic Imine analogue

SMILES CCOc1ccc(cc1)C1=N[C@@H]2[C@@]3(OC)C=C[C@@]4(C[C@@]13C)C1Cc3ccc(OC)c(O)c3C24CCN1C

InChI Key InChIKey=UBHZAZPYIIUMET-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286102   

TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286102(Morphinan Cyclic Imine analogue | CHEMBL353736)
Affinity DataIC50: 0.890nMAssay Description:Compound was tested for its ability to displace [3H]DAMGO from mu opioid receptor in hartley guinea pig brain membrane in the presence of 100 nM of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286102(Morphinan Cyclic Imine analogue | CHEMBL353736)
Affinity DataIC50: 12nMAssay Description:Compound was tested for its ability to displace [3H]Cl-DPDPE from delta opioid receptor in hartley guinea pig brain membrane in the presence of 100 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286102(Morphinan Cyclic Imine analogue | CHEMBL353736)
Affinity DataIC50: 97nMAssay Description:Compound was tested for its ability to displace [3H]U-69593 from Opioid receptor kappa 1 in hartley guinea pig brain membrane in the presence of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50286102(Morphinan Cyclic Imine analogue | CHEMBL353736)
Affinity DataIC50: 331nMAssay Description:Compound was tested for its ability to displace bremazocine from Opioid receptor kappa 2 in hartley guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article