BDBM50286589 (S)-5-{(S)-2-[Bis-((R)-sec-butyl)-amino]-1-hydroxy-ethyl}-1-(2-chloro-benzyl)-pyrrolidin-2-one::CHEMBL154309

SMILES CC[C@@H](C)N(C[C@H](O)[C@@H]1CCC(=O)N1Cc1ccccc1Cl)[C@H](C)CC

InChI Key InChIKey=YNGZJSALRCLELM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286589   

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286589((S)-5-{(S)-2-[Bis-((R)-sec-butyl)-amino]-1-hydroxy...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of [3H]dihydromorphine (1 nM) binding to mu opioid receptor of rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286589((S)-5-{(S)-2-[Bis-((R)-sec-butyl)-amino]-1-hydroxy...)
Affinity DataKi:  63nMAssay Description:Inhibition of 9 (2 nM) binding to Opioid receptor kappa 1 of rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286589((S)-5-{(S)-2-[Bis-((R)-sec-butyl)-amino]-1-hydroxy...)
Affinity DataKi:  265nMAssay Description:Inhibition of [3H]-[D-Pen2, D-Pen5]-enkephalin (2 nM) to Opioid receptor delta 1 of male Sprague-Dawley rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article