BDBM50287068 CHEMBL4172576::US10759787, Example 30::US11059811, Example 30
SMILES CCN(C1CCOCC1)c1cc2oc(cc2c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c1C)C#N
InChI Key InChIKey=GWWPLMJVLCHYQG-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50287068
TargetHistone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH1/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Human)
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Shanghai Hengrui Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human N-terminal His-tagged EZH2/flag-tagged EED/SUZ12/AEBP2/RBAP48 A677G mutant (2 to end residues) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:The activity of EZH2 enzyme (with A677G mutant or Y641F mutant) was tested by the following method.The method was used to determine the inhibitory ef...More data for this Ligand-Target Pair