BDBM50287332 1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-2-chloroacrylamide::CHEMBL289426

SMILES C=C(Cl)C(=O)N[C@@H]1CCC2C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)[C@H]1O5

InChI Key InChIKey=UDQTWCPWUCXLPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287332   

TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287332BDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 0.210nMAssay Description:Compound was tested for Inhibition of [3H]DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetDelta-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287332BDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 0.530nMAssay Description:Compound was tested for Inhibition of 9 (1 nM) binding to Opioid receptor delta 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287332BDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50: 1.5nMAssay Description:Compound was tested for Inhibition of [3H]-DPDPE (0.2 nM) binding to Opioid receptor kappa 1 from bovine striatal MembranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article