BDBM50287432 (S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2-phenyl-ethyl]-phosphinoylmethyl}-cyclopentanecarbonyl)-amino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL43114

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C1(CP(O)(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(cc2)[N+]([O-])=O)CCCC1

InChI Key InChIKey=JEFBYIWPDIJORK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287432   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 55nMAssay Description:Compound was measured for the inhibition of neutral endopeptidase 24.11(NEP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of phosphoramidon-sensitive membrane bound zinc metalloprotease Endothelin-converting enzyme from partially purified guinea pig l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287432((S)-2-[(1-{Hydroxy-[(R)-1-(4-nitro-benzoylamino)-2...)
Affinity DataIC50: 1.5nMAssay Description:Compound was measured for the inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article