BDBM50287469 CHEMBL4166984

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccc(CC4CCCCC4)c(c3)C#N)c(c2)C(F)(F)F)cc1

InChI Key InChIKey=WSGSDRXCOFGDEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287469   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50287469(CHEMBL4166984)
Affinity DataIC50: 79nMAssay Description:Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50287469(CHEMBL4166984)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bipheny...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed