BDBM50287491 CHEMBL295392::Inhibitors of MMP-1: An examination of P1' Calpha gem-disubstitution in the N-carboxyalkylamine and glutaramide carboxylate series

SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)CCCCC1

InChI Key InChIKey=JWGYJPREQNGRDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287491   

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287491(Inhibitors of MMP-1: An examination of P1' Calpha ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Matrix Metallo Proteinase-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article