BDBM50288947 CHEMBL158033::N*1*-((S)-1-{(2R,3S)-3-[(1-Isopropyl-2-methyl-propylcarbamoyl)-methyl]-oxiranyl}-2-phenyl-ethyl)-2-[(quinoline-2-carbonyl)-amino]-succinamide

SMILES CC(C)C(NC(=O)C[C@@H]1O[C@@H]1[C@H](Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(C)C

InChI Key InChIKey=GBYCHLWJCGXUHJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288947   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288947(N*1*-((S)-1-{(2R,3S)-3-[(1-Isopropyl-2-methyl-prop...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288947(N*1*-((S)-1-{(2R,3S)-3-[(1-Isopropyl-2-methyl-prop...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibitory activity against human cathepsin D was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article