BDBM50289330 6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazolo[3,2-b][1,2,4]triazole::CHEMBL155980

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2ncnn2c1-c1cc(F)cc(F)c1

InChI Key InChIKey=FZXHCCKCXBZUPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289330   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289330(6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50: >5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50289330(6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50:  7.94E+7nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50289330(6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-pheny...)
Affinity DataIC50:  80nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails Article