BDBM50289427 (R)-2-Amino-3-(4-phenoxy-phenylamino)-propane-1-thiol::CHEMBL26255

SMILES N[C@@H](CS)CNc1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=MWMQXYJKBYKXDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289427   

LigandPNGBDBM50289427((R)-2-Amino-3-(4-phenoxy-phenylamino)-propane-1-th...)
Affinity DataIC50: 460nMAssay Description:Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289427((R)-2-Amino-3-(4-phenoxy-phenylamino)-propane-1-th...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article