BDBM50289741 CHEMBL418106::[3-Oxo-4-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-5,6-dihydro-3H-benzo[h]cinnolin-2-yl]-acetic acid

SMILES OC(=O)Cn1nc-2c(CCc3ccccc-23)c(Cc2nc3cc(ccc3s2)C(F)(F)F)c1=O

InChI Key InChIKey=WDSIURMLIZMUHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289741   

LigandPNGBDBM50289741([3-Oxo-4-(5-trifluoromethyl-benzothiazol-2-ylmethy...)
Affinity DataIC50: 150nMAssay Description:Tested for inhibition of bovine lens Aldose reductase (ALR2), expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50289741([3-Oxo-4-(5-trifluoromethyl-benzothiazol-2-ylmethy...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity of compound against modified enzyme form of S-glutathionyl Aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article