BDBM50290635 CHEMBL422066::N-(3-Chloro-4-fluoro-phenyl)-N'-(6,7-dimethoxy-quinazolin-4-yl)-hydrazine

SMILES COc1cc2ncnc(NNc3ccc(F)c(Cl)c3)c2cc1OC

InChI Key InChIKey=DRGJAJGWXGZEPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290635   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290635(N-(3-Chloro-4-fluoro-phenyl)-N'-(6,7-dimethoxy-qui...)
Affinity DataIC50: 430nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290635(N-(3-Chloro-4-fluoro-phenyl)-N'-(6,7-dimethoxy-qui...)
Affinity DataIC50: 780nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article