BDBM50290637 (6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-amine::CHEMBL330323

SMILES COc1cc2ncnc(Nc3nccc4ccccc34)c2cc1OC

InChI Key InChIKey=CCFFFEGDTIMEEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290637   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290637((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-a...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In DepthDetails Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290637((6,7-Dimethoxy-quinazolin-4-yl)-isoquinolin-1-yl-a...)
Affinity DataIC50:  200nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails Article