BDBM50290639 Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin-4-yl)-amine::CHEMBL90541

SMILES COc1cc2ncnc(Nc3nnc4ccccc4n3)c2cc1OC

InChI Key InChIKey=ZOMDZHXLXCJKSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290639   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290639(Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 820nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290639(Benzo[1,2,4]triazin-3-yl-(6,7-dimethoxy-quinazolin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article