BDBM50290640 (6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopropyl)-amine::CHEMBL419137

SMILES COc1cc2ncnc(NC3CC3c3ccccc3)c2cc1OC

InChI Key InChIKey=DFMLKCNZXJFCBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290640   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290640((6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopro...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290640((6,7-Dimethoxy-quinazolin-4-yl)-(2-phenyl-cyclopro...)
Affinity DataIC50: 140nMAssay Description:Inhibition of EGF-stimulated proliferation of KB cells in cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article