BDBM50290955 CHEMBL96662::N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-pyridazin-1-yl)-acetyl]-4-bromo-benzenesulfonamide

SMILES Cc1ccc(=O)n(n1)C(C(=O)NS(=O)(=O)c1ccc(Br)cc1)c1ccc2OCOc2c1

InChI Key InChIKey=HQJLENNQWLKHGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290955   

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50290955(N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-py...)
Affinity DataIC50: 230nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to the endothelin A receptor of rat aorta membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50290955(N-[2-Benzo[1,3]dioxol-5-yl-2-(3-methyl-6-oxo-6H-py...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of specific binding of [125I]ET1 (endothelin 1) to endothelin B receptor of porcine kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article