BDBM50290976 1-[Methyl-((1S,2S)-2-pyrrolidin-1-yl-cyclohexyl)-carbamoyl]-2,3-diphenyl-cycloprop-2-enecarboxylic acid methyl ester::CHEMBL329755

SMILES COC(=O)C1(C(=O)N(C)[C@H]2CCCC[C@@H]2N2CCCC2)C(=C1c1ccccc1)c1ccccc1

InChI Key InChIKey=LLHSWSRTBINBNJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290976   

TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290976(1-[Methyl-((1S,2S)-2-pyrrolidin-1-yl-cyclohexyl)-c...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article