BDBM50291255 CHEMBL358623::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-(2-methyl-propenyl)-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate

SMILES CC(C)=Cc1sc(C(C)C)c(/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])c1-c1ccc(F)cc1

InChI Key InChIKey=AONJUGYYEQTDKH-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291255   

LigandChemical structure of BindingDB Monomer ID 50291255BDBM50291255(Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopr...)
Affinity DataIC50: 15nMAssay Description:Tested in vitro for the HMG-CoA reductase inhibitory activity in a microsomal preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article