BDBM50292971 CHEMBL454132::N-(((1R,2S,5S)-3-(2-(3-hydroxypropyl)-5-m-tolylthiazole-4-carbonyl)-3-azabicyclo[3.1.0]hexan-2-yl)methyl)-6-methylimidazo[2,1-b]thiazole-5-carboxamide

SMILES Cc1nc2sccn2c1C(=O)NC[C@@H]1[C@@H]2C[C@@H]2CN1C(=O)c1nc(CCCO)sc1-c1cccc(C)c1

InChI Key InChIKey=JEAVKGWTICGJLV-VAMGGRTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292971   

TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292971(CHEMBL454132 | N-(((1R,2S,5S)-3-(2-(3-hydroxypropy...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at OX2 receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292971(CHEMBL454132 | N-(((1R,2S,5S)-3-(2-(3-hydroxypropy...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at OX1 receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed