BDBM50293247 CHEMBL468970::N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3,5-dimorpholinophenyl)pyrimidine-2,4-diamine
SMILES Clc1ccc2OCOc2c1Nc1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1
InChI Key InChIKey=IVXGFXACZQBKSB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50293247
Affinity DataIC50: 17nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair