BDBM50293248 3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimidin-2-ylamino)-5-morpholinobenzamide::CHEMBL517720

SMILES NC(=O)c1cc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc(c1)N1CCOCC1

InChI Key InChIKey=IITDSYICYIVZSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293248   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293248(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293248(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 887nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed